Prenetics partners with Watsons, one of Asia’s largest personal care retailers, to sell its new consumer DNA tests

Genetics testing startup Prenetics today announced a major new deal for its brand in Asia. The company is partnering with A.S. Watson Group, the personal care giant whose stores are ubiquitous in many East and Southeast Asian countries. That means Watsons’ Hong Kong stores and website will be the first retailer in Asia to sell Circle DNA, Prenetics’ new consumer DNA testing kit, before it launches in Watsons’ other Asian markets.

Watsons has 15,200 stores in 25 countries across Asia and Europe, including Hong Kong, China, Taiwan, Indonesia, Malaysia, Singapore, Ukraine and Russia, and claims to be the largest health and beauty retailer in the world. Also based in Hong Kong, Prenetics began by providing DNA tests for insurance firms and health care providers, before branching into consumer tests by buying London-based startup DNAFit last year. The acquisition of DNAFIt, which still sells testing services under its own brand, also gave Prenetics a foothold in the U.S., where DNAFit is partnered with Helix, another gene testing company.

Prenetics launched in 2009 and has raised more than $50 million so far from investors including Beyond Ventures and Alibaba Hong Kong Entrepreneurs Fund, who led its $40 million Series B in 2017.

As it expands, Prenetics will become a more direct competitor with companies like 23andMe and AncestryDNA. Circle DNA’s kits differentiate by focusing primarily on health reports instead of ancestry. The most important advantage a DNA test can offer, however, is accuracy, and the ability of consumer DNA tests to answer certain questions reliably has been called into question by geneticists. Prenetics claims its technology, which uses whole exome sequencing instead of genotyping, is able to provide 50 to 100 times more data than competing tests.

In a press statement, A.S. Watson Group chief operating officer Malina Ngai said “We are excited to launch Circle DNA first in Watsons Hong Kong, providing an easy solution for personalized digital healthcare assessment. Combined with our strong customer connectivity, scalable pharmacy network, professional health team and loyalty program, we are committed to help customers to take further actions to improve their known health concerns.”

23andMe updates its ancestry reports, but they’re still not perfect

23andMe, co-founded by CEO Anne Wojcicki, has deployed its latest update, featuring interactive ancestry details, cultural insights about food, art, language, and the option to order a physical ancestry book. Starting today, customers will be able to see more granular ancestry results from more than 1,000 regions, as well as 33 population-specific pages about cultural information.

Before this update, 23andMe simply said I was 12 percent Brtish and Irish. Now, it’s able to break down where in the U.K. my ancestors likely lived. 23andMe, however, was not able to detect more granular data in Ireland.

It was also unable to detect additional evidence in Nigeria, where 23andMe says 25.2 percent of my ancestry comes from. That’s likely because, even though 23andMe has made efforts to grow the number of African and African-American people in its dataset, it’s still lacking. Though, it’s worth noting no ancestry service has it all.

“The odds of receiving more granular results from a particular region (in your particular case, Ireland or Nigeria) depends on how much Nigerian DNA someone has and how many individuals are in the 23andMe reference dataset,” 23andMeAncestry Group Product Manager Robin Smith told TechCrunch. “The reference dataset is continuously growing, and customers should be seeing even more refined ancestry results later in the year.”

Generally speaking, customers who share exact matches between their DNA and reference individuals from a particular region could potentially see granularity in regions of Anambra, Edo, Imo, Lagos and Ogun State in Nigeria, 23andMe spokesperson Christine Pai told TechCrunch.

It’s worth noting Ancestry says I have just 1 percent of my DNA comes from Nigeria and that the bulk of my African ancestry comes from Cameroon and Congo. But when I first signed up for Ancestry, the company said 39 percent of my ancestry came from Nigeria. This is all to say that these tools are imperfect and always subject to change. And, depending on where the bulk of your ancestry comes from, it may change dramatically.

“I’m not surprised you’ll get different results from different companies,” Dr. Jennifer Raff, Assistant Professor in the Department of Anthropology at the University of Kansas told TechCrunch back in September. “They have their own proprietary info based on those samples. If one of them has lots of individuals from a particular region and the other company does not, you’re more likely to show up as having ancestry from that region whereas if the other company doesn’t have that data represented in their database, it’s going to show up as a different population.”

This is problematic, given many people turn to these DNA testing tools to figure out more about who they are and where they come from. I’ll keep this brief, but I was pretty frustrated when I went from thinking I was very Nigerian (39 percent, according to Ancestry) to barely Nigerian (about one percent, also according to Ancestry) to then again a fair amount of Nigerian (25 percent, according to 23andme).

“This is a problem and it’s one we need to educate people about — that your genetic ancestry is not your identity,” Dr. Raff said. “Also, those numbers really reflect what is in their database, and what’s in the database is largely reflective of genetic variations we see in present-day populations. That doesn’t necessarily mean it’s reflecting your actual ancestors.”

I asked Dr. Raff if DNA testing is just a load of crock, but she said it’s not.

“It’s not complete bullshit but there’s also a lot of uncertainty there,” she said. “We [humans] like definitive answers. We’re trying to use this as a tool for exploring our past. We like to have definite answers when we’re doing these explorations, but unfortunately, it’s not there yet.”

But that’s not entirely the fault of 23andMe and Ancestry. In order to be as accurate as humanly possible, these companies would need to sequence every person on the planet. That’s not currently feasible, so in the meantime, Ancestry points to its confidence levels.

“We take this pretty seriously and we do want people to understand what is something they can put money in the bank on, and what they should take with a grain of salt,” Ancestry Chief Scientific Officer Catherine Ball told TechCrunch back in September.

She added that Ancestry tries to be transparent about confidence levels. And, in Africa specifically, “it’s one of our most exciting opportunities and greatest challenge” due to the enormous amount of genetic diversity on the continent.

Additional reporting by Sarah Buhr.

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